Knoxville vs Panama City for Nurses (2026)

Better for nurses: Panama City~33% cheaper overall
State Income Tax
None
Knoxville
None
Panama City
Est. Monthly Take-Home (RN)
$6,896
Knoxville
$6,896
Panama City
1BR Rent / month
$1,300
Knoxville
$900
Panama City
1BR Rent Burden (% of take-home)
19%
Knoxville
13%
Panama City

Scroll down for travel nurse analysis, rent burden, and FAQ.

Nurse salary cost breakdown

Metric
Knoxville
Tennessee
Panama City
Panama Province
State income taxNoneBetterNone
Est. monthly take-home ($82.75K RN)$6,896Better$6,896
1BR rent / month$1,300$900Better
1BR rent burden19%13%Better
Internet / month$60$40Better
Monthly utilities$168$70Better
Walk score26 / 10065 / 100Better
Overall COL index (100 = US avg)8758Better
Financial Wins

Your biggest money opportunities based on this comparison.

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Savings potential

Panama City: ~$5,532/mo after rent & living

Nurses with strong take-home can build wealth fast. Compare brokers and robo-advisors to put it to work.

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Renters insurance

Panama City saves ~$400/mo in rent

Protect your home — nursing shifts are long and you want peace of mind when you're away.

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Complete the Picture

While you're comparing — don't leave money on the table.

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Mortgages

See what you can afford in Panama City

Compare rates from top lenders before your move — pre-approval is free and won't affect your score.

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Home & Auto Insurance

Bundle before you move — save 15–25%

New state means new rates. Lock in Panama City homeowners + auto quotes before your move date.

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Frequently asked questions

Which city is better for nurses — Knoxville or Panama City?

For nurses, Panama City is the stronger choice based on take-home pay after taxes, rent burden, and cost of living. The key differentiator is rent: Panama City has lower 1BR rents. For travel nurses specifically, no-income-tax states are especially valuable since housing stipends are already tax-exempt — earning more in a no-tax state can be worth $3,000–$6,000/year more in take-home pay.

How much take-home pay does a nurse earn in Knoxville vs Panama City?

Based on the national average RN salary of $82,750/year, a nurse in Knoxville (no state income tax) takes home approximately $6,896/month. In Panama City (no state income tax), take-home is $6,896/month — a difference of $0/month or ~$0/year. Note: this calculation uses state income tax only; federal taxes are not included.

What percentage of a nurse's income goes to rent in Knoxville vs Panama City?

Financial advisors recommend keeping housing under 30% of gross income. In Knoxville, rent consumes 19% of a nurse's monthly take-home — very affordable, leaving significant room to save. In Panama City, rent burden is 13% — very affordable.

Is Knoxville or Panama City better for travel nurses?

Travel nurses on assignment typically receive a base wage PLUS a tax-free housing stipend (usually $1,500–$3,000/month) that covers housing costs. For travel nurses, the state income tax on the base wage is the primary cost difference. Knoxville is more advantageous. The housing stipend covers most rent — so the $0/month tax difference goes directly into savings, compounding over a 13-week assignment to $0 extra in take-home.

How does the cost of living affect a nurse's purchasing power in Knoxville vs Panama City?

A $82,750 nurse salary in Panama City (COL 58) has the equivalent purchasing power of $124,125 in Knoxville (COL 87). The lower-cost city effectively gives nurses a ~50% raise with no salary negotiation required — more savings, faster debt payoff, and greater financial flexibility.

Estimated monthly savings after rent
Knoxville
$4,900
after rent + basic living
Panama City
$5,532
after rent + basic living
Related comparisons

Nurse salary based on national median RN wage ($82,750/year, BLS 2024). Take-home calculated using state income tax rate only; federal taxes not included. Travel nurse stipend rules vary by assignment and employer. Data: BLS, Zillow, Tax Foundation · Q1 2026